abstract |
(57) [Summary] (Modified) [Objective] A composition for sustained and controlled release of medicinal peptide substances, obtained in the form of microspheres of biodegradable polymeric substances loaded with medicinal substances. I will provide a. The above composition is obtained by first converting a water-soluble peptide or peptide salt into a water-insoluble peptide or peptide salt, respectively, and then forming an organic aqueous emulsion, and extracting an organic solvent in an excess of an aqueous medium. To be |