| abstract |
(57) [Summary] (Modified) [Objective] A compound showing useful pharmacological actions including a potassium channel activating action and a 5-lipoxygenase inhibitory action, and particularly useful as a smooth muscle relaxant and a bronchodilator. provide. [Constitution] The following formula (I) [Wherein R 1 and R 2 are hydrogen, lower alkyl, etc., R 3 Is hydrogen, halogen, fluoro lower alkyl, etc., and R 4 is R 5 and R 6 are hydrogen or lower alkyl, R 7 is —NR 8 R 9 and R 8 represent hydrogen, lower alkyl, lower alkoxy, etc., and R 9 represents hydrogen, lower alkyl, hydroxy lower alkyl, etc.] or a pharmaceutically acceptable salt thereof. |