abstract |
(57) [Summary] [Structure] General formula [Chemical formula 6] [W: -O -, - S- , X: -NR 1 - or W: - NR 1- , X: -O-, -S-; R 1 : H, C 1 -C 6 Alkyl, substituted C 1 -C 4 alkyl; R 2 , R 3 : H, C 1 -C 6 alkyl, substituted C 1 -C 4 alkyl, aryl, aromatic heterocycle; R 4 : H, C 1 -C 6 Alkyl, substituted C 1 -C 4 alkyl; A: optionally substituted C 2 -C 6 alkylene], thia or oxazolidinone derivative. [Effect] This compound has an excellent collateral vasodilator effect and is useful as an antianginal agent. |