abstract |
(57) [Summary] [Object] The present invention aims to provide an antibody specific to different human T cell antigen receptor chains. The present invention is a recombinant DNA comprising a chimeric nucleotide encoding a sequence for a T cell antigen receptor β chain, the sequence comprising; all variable regions (Vβ2) and its head. Human-derived coding sequences for sequences, changes (Dβ) and junctions (Jβ), and constant complements (Cβ) not present in the human sequences And (β2), which comprises a murine-derived coding sequence, the two sequences being linked at the level of a restriction site, either natural or artificial. |