| abstract |
(57) [Summary] (Modified) [Objective] To provide sulfonamides having antifungal activity. A compound of formula I, a compound of general Ia in which it is cyclized to isooxozolidine, and pharmaceutically acceptable salts thereof, a process for their preparation, and pharmaceutical and agrochemical compositions containing the above compounds object [Wherein X is N, CH; R 1 is C 1-6 alkyl, 1, 2,4-triazol-1-yl-C 1-6 alkyl, Phenyl -C 1-4 alkyl or the like; R 2 is H, C 1-6 alkyl, phenyl -C 1-4 alkyl, Ikowa (pyridyl, furyl, Choi two Lucia benzisoxazolyl) -C 1-4 alkyl such as; R 3 is hydrogen; R 4 is hydrogen or (1H-1,2,4- Triazol-1-ylmethyl); R 5 is hydrogen, C 1-6 alkyl, (substituted) phenyl; R 7 is hydrogen, C 1-6 alkyl; Ar is (one or more halo, CF3 substituted) Phenyl group] |