| abstract |
(57) [Summary]n[Objective] The present invention provides a virus having a novel structural unit. A novel inhibitor of aspartic protease For the purpose of providing.nThe present invention provides the following formula In[Chemical 1]n (In the formula; R 1 Is tertiary butoxycarbonyl, benzyloxy Amino linked via carbonyl, carboxy Valine monovalent group; or phenyl-, 3-pyridyl- Acetyl, morpholino, thiomorpholino, butyrate One of xy-carbonyl and benzylcarbonyl Attached via a carboxy group on the nitrogen atom by Is an acylated alanine group, R 2 ， R Four , R 6 And R 8 Is hydrogen and R 3 Is benzyl R Five Is hydroxy and R 7 Is isobutyl, chrysanthemum Rohexylmethyl or benzyl, and R 9 Is R 1 Is one of the groups described above for) And a pharmaceutically acceptable salt thereof. It |