http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H05194592-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 1992-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_191d15a69f2210c68bc03c25dd2cee3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afd185a76a2c484d2b9ac3d360486e03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0996f5ed72d18ebd2f31194d9a6842 |
| publicationDate | 1993-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H05194592-A |
| titleOfInvention | Peptide derivative and its use |
| abstract | (57) [Summary] [Purpose] The creation of novel peptide derivatives having endothelin receptor antagonistic activity. [Structure] General formula [Chemical formula 1] [In the formula, A is a D-acidic-α-amino acid residue, and B is a D-neutral- α-amino acid residue, C is L-α-amino acid residue, D is a D-α-amino acid residue having an aromatic ring group, R 1 is a hydrogen atom or an optionally substituted amino group, R 2 is a carboxyl group which may be amidated or esterified, m and n each represent 1 or 2] or a salt thereof. [Effect] It has a remarkable endothelin receptor antagonistic action, and is useful as a drug such as a therapeutic agent for hypertension, a therapeutic agent for cardio-cerebral circulation disease, a therapeutic agent for renal disease and the like. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110199604-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110199604-B |
| priorityDate | 1991-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.