http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H05194299-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f8cfa5aee4410611b5c562275c9f8e3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1992-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aee120f901a493afd450f124d55a3c41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97919778aa695c9d253ff677d65d0547 |
| publicationDate | 1993-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H05194299-A |
| titleOfInvention | Optically active glycidol derivative and method for producing the same |
| abstract | (57) [Summary] [Object] To provide an inexpensive synthetic method of an optically active glycidol derivative having a protecting group which is stable under various reaction conditions and which can be removed under mild conditions. [Structure] 1-halogeno-3- (4-methoxyphenyloxy) -2-propanol having a racemic or low optical purity represented by the general formula (3) is reacted with vinyl acetate in an organic solvent using lipase as a catalyst. , (R) -1-halogeno-3- (4-methoxyphenyloxy) -2-propylacetate represented by the general formula (2) and (S) -1-halogeno-represented by the general formula (1). 3- (4-Methoxyphenyloxy) -2-propanol was obtained, and this compound was further reacted with an alkali in an organic solvent to give a compound of formula (4) (R) -O- (4-methoxyphenyloxy) glycidol represented by or (S) -O- represented by formula (5) (4-Methoxyphenyloxy) glycidol is obtained. [Chemical 1] (In the formula, X represents a halogen atom and Ac represents an acetyl group.) |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008100944-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113278197-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101106804-B1 |
| priorityDate | 1992-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.