| abstract |
(57) [Summary] [Object] To provide a water-soluble composition containing a sustained pharmaceutically active substance. [Structure] (a) Other than erythropoietin, a pharmaceutically active substance that is a peptide secreted by the living body or a derivative thereof, or a chemically synthesized pharmaceutically active substance, (b) water-soluble hyaluronic acid, and (c) substantially no pharmacological activity. A water-soluble composition containing a water-soluble protein that can be injected into a body fluid. [Effect] The in-vivo effect of the pharmaceutically active substance is enhanced, and even a thin injection needle can be administered, which alleviates the pain of the patient. |