| abstract |
(57) [Summary] [Structure] A physiologically active substance such as lactic acid bacterium and bifidobacteria is used as an agglomerate, and the agglomerate is a layer containing (A) oil and fat and an excipient, (B) zein, etc. Of the hydrous alcohol-soluble protein and the (C) sugar-containing layer. [Effect] Since the granulated product is not dissolved in the stomach but is dissolved in the intestinal tract, the physiologically active substance can exert its physiological activity in the intestinal tract without being affected by the low pH gastric juice. it can. Further, by providing a sugar coating layer ((C) layer), Good smoothness with a smooth surface. |