abstract |
(57) [Summary] (Modified) [Structure] A trifluorothymidine derivative represented by the general formula (1), a method for producing the same, and an antitumor agent containing the same. (In the formula, R 1 represents a hydrogen atom, a substituted silyl group or a substituted or unsubstituted trityl group, and R 2 represents an aldose residue, or a lower acyl group, a substituted or unsubstituted benzoyl group, an arylmethyl group and Represents an aldose residue substituted with either a benzylidene group or a deoxyaldose residue substituted with a phthaloylamino group.) [Effect] This compound has low toxicity and strong antitumor activity. It is useful as a tumor agent. |