Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
1992-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e8b3f83f78fd967fee9a8d4348b3c4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d284c2724df617b87b61847e479d549d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d773fced85d4abb2eeb0bfccc1b7f19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0b275d88d481be5ba3b2e301714807e |
publicationDate |
1993-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H05168499-A |
titleOfInvention |
Membrane-bound probe |
abstract |
(57) [Summary] [Object] The object of the present invention is to provide an oligonucleotide probe reagent useful for the diagnosis of infectious diseases and genetic diseases, and a method for producing the same. The probe reagent of the present invention comprises a nylon membrane having a high density of anionic carboxyl groups and at least one kind of oligonucleotide probe containing a 5 ′ amine covalently bound via an amide bond. It consists of [Effect] The single 5′-end binding of the oligonucleotide to the membrane surface increases the hybridization efficiency of the oligonucleotide probe and improves the reproducibility and sensitivity of the reagent. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004041109-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006304810-A |
priorityDate |
1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |