abstract |
(57) [Summary] (Correction) [Constitution] The following formula (I) (In the formula, R 1 and R 2 are the same or different and are lower alkyl groups, or together form a ring which may have a substituent, and X represents a methylene group or —CH═CH—, n represents an integer of 1 to 3, Y represents a sulfur atom, an oxygen atom, a sulfoxide group, a sulfone group, a methylene group, a carbon atom substituted with a lower alkyl group, or a nitrogen atom substituted with an aralkyl group or a lower alkyl group. The present invention relates to a substituted pyrimidinone derivative represented by the formula (1) and an antiulcer agent containing the same. [Effect] The compound of the present invention has a strong inhibitory action on gastric acid secretion and a potentiating action on defense factors, and is also highly safe, so that it is useful as an excellent anti-ulcer agent. |