| abstract |
(57) [Summary] (Modified) [Structure] 17-allyl or ethyl-1,14-dihydroxy-12- [2- (4-hydroxy-3-methoxycyclohexyl) -1-methylvinyl] -23,25 − Dimethoxy-13,19,21,27-tetramethyl- 11,28-dioxa-4-azatricyclo [22. 3.1.0 4,9 ] Octacos-18-ene-2,3,1 A suspension composition comprising a tricyclo compound represented by 0,16-tetraone or a salt thereof, a fine powder having an average particle size of 5 μm or less, a pharmaceutically acceptable surfactant, and optionally an aqueous medium. .. [Effect] The above-mentioned tricyclo compound and its medically acceptable salt have excellent immunosuppressive action and antibacterial action, and this suspension composition is useful as an oral preparation or an eye drop. |