| abstract |
(57) [Summary] (Modified) [Objective] To provide novel synthetic antibiotics, precursors thereof, and methods for producing them. [Structure] The following general formula (1): [Wherein R 1 is a C 1-4 alkoxy group, a C 1-4 alkylthio group, —NHCHO; R 2 is H, a carboxy protecting group; R 2 ′ is H, OH, C 1-5 (halo) alkyl group, C 1-5 alkoxy group, CN, etc .; R is a carboxylic acid residue] By synthesizing acids, it was shown that these compounds inhibit the growth of many pathogenic microorganisms. |