| abstract |
(57) [Summary] (Corrected) [Configuration] General formula below (Y and B can be omitted) [wherein E is O or S; A is a saturated C 1 -C 14 alkylene having a linear or branched structure; Y is oxygen, sulfur, sulfinyl, or sulfonyl] Yes; B is a linear or branched saturated C 1 -C 14 alkylene; D is a linear or branched saturated or unsaturated C 1 -C 4 alkyl; CF 3 , -CHF 2 , -CH 2 F, or phenyl D 1 is H, -CF 3 , -CHF 2 , -CH 2 F, -CH. 3 or phenyl]. [Effect] The above compounds are useful as inhibitors of cholesterol biosynthesis and as agents for lowering total serum cholesterol. |