abstract |
(57) [Summary] (Modified) [Configuration] The following formula: (In the formula, R 1 is aryl optionally substituted with halogen or the like, R 2 is lower alkyl optionally substituted with a substituent such as cyclo (lower) alkyl, and R 3 is a substituent such as halogen. Optionally substituted aryl, etc., R 4 is lower alkyl, etc., R 5 is hydrogen, etc., A is a single bond, etc., and X is O, etc., and a process for producing the same. An ACAT inhibitor containing as an active ingredient. [Effect] A drug containing the above compound as an active ingredient is useful for preventing and treating hypercholesterolemia, hyperlipidemia, and atherosclerosis. |