abstract |
(57) [Summary] [Structure] A method for producing a lactone, which comprises performing an intramolecular esterification reaction of a hydroxy acid or a derivative thereof in the presence of a solid catalyst. As the solid catalyst, hydrous zirconium oxide, zeolite, SiO 2 —Al 2 O 3 , silica, alumina and MgO can be used. [Effect] Medium-sized macrocyclic lactone can be efficiently produced. Further, since the solid catalyst is a heterogeneous catalyst, it is easy to handle and can be easily separated from the reaction product. And it can be used repeatedly. Furthermore, it has no impact on the environment. |