abstract |
(57) [Summary] [Object] To provide a transgenic mouse in which a human ADF gene is introduced and the gene is highly expressed. [Constitution] A target transgenic mouse is prepared by using a gene fragment having a promoter, a human ADF gene, a translation termination codon, a poly A signal, and a terminator in this order from the 5'end. [Effect] The human ADF transgenic mouse can be used for elucidation of the mechanism against external stress. |