abstract |
(57) [Summary] (Modified) [Structure] A novel pharmaceutical composition containing a phosphatidylserine represented by the general formula (I) and some chemical compound analogues. Wherein, X is H, -COOH; A is - (CH 2) n -O -CO-R (however, n = 1, 2), -CH (O-CO- R) -CH 2 -O-CO- R; B is - (CH 2) m -O Y (however, m = 1, 2, 3, 4), etc., where Y is H, -C OR: -CO-R represents an aliphatic, aromatic, alicyclic or heterocyclic acyl group] [Effect] The involvement of tumor necrosis factor has been confirmed in the pharmaceutical composition of the present invention. It is suitable for the pharmacological treatment of various degenerative lesions associated with autoimmune deficiency, such as multiple sclerosis (MS) and various other (neuropathological) phenomena. |