| abstract |
(57) [Summary] (Modified) [Objective] To provide a salt of a basic histamine H 2 -receptor antagonist and a bismuth carboxylate complex. [Structure] A furan derivative represented by the general formula (I) having an antagonistic effect on a histamine H 2 -receptor and a bismuth complex of a carboxylic acid selected from tartaric acid, citric acid and alkylcitric acid are preferably used as water. Salts obtained by reacting in various solvents or solvates of the salts, and pharmaceutical compositions containing the salts. [Wherein R 1 is —C (═CHNO 2 ) NHCH 3 , 1-methyl-3-hydroxymethyl-1,2,4-triazol-5-yl, etc .; R 2 is hydrogen or methyl; X is oxygen; (N = 3 in this case), sulfur or CH 2 (n = 2 in these cases). [Effect] These salts and solvates are gastrointestinal disorders such as peptic ulcer, gastritis and non-ulcer dyspepsia. It is useful for the treatment of |