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filingDate 1992-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1993-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H05105627-A
titleOfInvention Novel pharmaceutical composition used for treatment of intestinal dysfunction, preparation method thereof, and preparation method of therapeutic drug
abstract (57) [Summary] (Modified) [Objective] A novel pharmaceutical composition used particularly for the treatment of intestinal dysfunction, a method for preparing the same, and a method for preparing a medicament for the treatment of the above diseases. [Structure] A mixture of [R] amino acid derivative of acetorphan and [S] amino acid derivative, particularly a mixture of enantiomers, wherein the ratio of [R] derivative to [R] + [S] is 65 ± 15% to 20%. A novel pharmaceutical composition applicable to long-term treatment of intestinal irritable syndrome (however, excluding 50% mixture). [R] derivative: [S] derivative:
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