| abstract |
(57) [Summary] (Modified) [Purpose] Substituted sulfonamide derivatives and their acid addition salts useful as active ingredients of therapeutic and prophylactic agents for respiratory diseases such as asthma, and useful containing them. A pharmaceutical composition is provided. [Structure] A substituted sulfonamide derivative represented by the following formula and an acid addition salt thereof. [In the formula, A is hydrogen or a lower alkyl group, B is an alkylene group, C is an ethylene group, D is an ethylene group or trimethylene group, E is an alkyl group, and X is a group represented by the following formula. R 1 represents hydrogen, halogen or a lower alkyl group, and R 2 represents hydrogen or a hydroxyl group.] |