http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0499718-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03d0f52bb4069f8a19d70dcfb697c67a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52 |
| filingDate | 1990-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71a6b3c6ca4ea28277596b168d5160cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6ca6d7721dae6c76f9aa163ea21029b |
| publicationDate | 1992-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0499718-A |
| titleOfInvention | Production of surface-modifiable liposome and surface-modified liposome |
| abstract | PURPOSE: To obtain a surface-modifiable liposome capable of immobilizing various substrates according to simple operation under mild conditions by embedding a long-chain active amide having hydrophilic leaving groups in a liposome bimolecular membrane. n CONSTITUTION: A surface-modifiable liposome is constructed from a compound expressed by the formula (R 1 is hydrophobic group; R 2 and R 3 are H, organic group or may be mutually linked to form a ring or double bond; Y is O or S; Z is hydrophilic group; W is linking group; n is 0 or 1) and a lipid capable of forming the liposome. The molar ratio of the compound expressed by the formula based on the total constituent material is preferably ≤50%, especially preferably ≤35%. A surface-modified liposome is obtained by mixing the above-mentioned liposome with a substrate having amino groups and/or thiol groups and immobilizing the aforementioned substrate on the surface thereof. A similar surface-modified liposome can be obtained by binding the compound expressed by the formula to the substrate having the amino groups and/or thiol groups and mixing the resultant compound with the lipid capable of forming the liposome. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008117334-A |
| priorityDate | 1990-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.