http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0489456-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 |
| filingDate | 1990-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b01fb5939f54da52f377c088538d663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceac8f179a4385147af549a8292c2d34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ce006ca9aa70baca987d9e1e4930f81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5396d9847ac39e91ab6a58c40935253 |
| publicationDate | 1992-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0489456-A |
| titleOfInvention | Novel water-soluble vitamin k derivative and its production |
| abstract | NEW MATERIAL:The compound of formula I (X is group of formula II or formula III, or its pharmacologically permissible salt. n EXAMPLE: Phyllohydroquinone-di-hemifumarate disodium salt. n USE: A medicine. A medicine of a stable water-soluble reduced-type vitamin K, capable of solubilizing vitamin K without using a surfactant and a dissolution assistant, reducible in living body to exhibit the activity of reduced-type vitamin K and useful as a preventive and therapeutic agent for diseases or symptoms caused by the deficiency of vitamin K. It is also used as a preparation containing a fat-soluble vitamin K in the form soluble in water. n PREPARATION: The objective compound of formula I can be produced either by condensing a compound of formula II with a compound of formula III in a solvent in the presence of a base or by carrying out the condensation reaction and deprotection reaction. The starting compound of formula II can easily be produced at a low cost by reducing phylloquinone or menaquinone. The compound of formula I can be converted to the salt by reacting with a salt such as a solution of NaOH. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6184255-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9807417-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-714644-B2 |
| priorityDate | 1990-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.