http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0477452-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
filingDate | 1990-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78ccee4e8e71f8e7737528c7126b6033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0860423a8409cb78897633e3b362f2ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b77fae697ed6aa65b3714a3a443ddf6 |
publicationDate | 1992-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H0477452-A |
titleOfInvention | Production of cyclooctane derivative |
abstract | PURPOSE: To efficiently obtain the title compound in one step from industrially readily available raw materials, useful as an intermediate for advantageously producing prostaglandins by reaction of cyclooctanone with succinic anhydride in the presence of lithium compound(s). n CONSTITUTION: (A) Inexpensive cyclooctanone is reacted at pref. -80 to 25°C with (B) pref. 0.75-1.25 molar times of succinic anhydride in the presence of (C) pref. 0.75-1.25 molar times of lithium compound(s) (e.g. lithium disopropylamide, n-, sec- or tert-butyllithium and/or methyllithium; pref. lithium diisopropylamide), thus obtaining in an industrially advantageous way the objective compound of the formula useful as an intermediate for 7-(2,5- dioxocyclopentyl)heptanoic acid(an intermediate capable of producing cyclopentenyl derivatives as prostaglandins in two to three steps in high yield). n COPYRIGHT: (C)1992,JPO&Japio |
priorityDate | 1990-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.