| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98cb1b197f761c87cd3caf32bc247e2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02 |
| filingDate |
1990-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a10ca44e1eaaaac8aafb0534b270adf1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7261122c36538ffaa01b89de86369287
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f769258c87387dc0c2cb5525b2b1880
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_def565d811b20ed693f5ba206d5650e5 |
| publicationDate |
1992-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H0466575-A |
| titleOfInvention |
2-nitromidazole derivative and antiprotogoal containing the same derivative |
| abstract |
NEW MATERIAL:2-Nitroimidazole-1-propionohydroxamic acid shown by formula I. n USE: An antiprotogoal showing high medicinal effects on Trypanosoma cruzi of mastigote and useful as a remedy for chagasi disease, having a little side effects and simply usable. n PREPARATION: 2-Nitroimisazole shown by formula II is reacted with an alkyl acrylate shown by formula IV (R is lower alkyl) in the presence of a base (e.g. triton B) at 80-100°C to give a compound shown by formula III. Then this compound is reacted with hydroxylamine or a derivative thereof in a solvent such as methanol at 0-35°C to give a compound shown by formula I. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013122112-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9655975-B2 |
| priorityDate |
1990-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |