http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H045266-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e29e759d65b7e915908ffc01c56b2c6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 |
| filingDate | 1990-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f914153ccca7474f80610170dce408c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72d52dc880ab4a313472be3526f56c47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3d1ebaf241446dae828c086fa35bf2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c596b82a3fd8233d4bffab4874a736fb |
| publicationDate | 1992-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H045266-A |
| titleOfInvention | Production of dopamine derivative |
| abstract | PURPOSE: To industrially advantageously obtain the subject compound by reacting an ethylamine derivative corresponding to the aimed compound with a butane-2-one derivative in the presence of a boron cyanated sodium hydride catalyst and subjecting resultant new intermediate to demethylation. n CONSTITUTION: A compound expressed by formula I is reacted with a compound expressed by formula II in an organic solvent, preferably alcoholic solvent, etc., and in the presence of a boron cyanated sodium hydride catalyst to obtain a new substance expressed by formula III. Next, the new substance is subjected to demethylation in a normal method and further an acid is added, as necessary, to afford the aimed compound expressed by formula IV or acid-added salt of the compound useful for treating abruptly depressed cardiac contraction with a few processes and simple and safe process in high yield. Besides, to the compound expressed by formula II, the compound expressed by formula I is preferably used as equimolar to 8 times mol, especially 4-6 times mol and the catalyst is preferably used as equimolar to 5 times mol, especially equimolar to two times mol. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9796672-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11691947-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10611728-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9346114-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9815770-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014524482-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11214540-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10207991-B2 |
| priorityDate | 1990-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.