| abstract |
PURPOSE: To obtain an external preparation of suppressing melanogenesis, extremely inhibiting melanogenesis, showing excellent beautifying effects and anti-sunburning effect, having high safety, comprising 2-, 3- or 4-hydroxybutyric acid or sodium salt thereof as an active ingredient. n CONSTITUTION: An external preparation such as cosmetic base or ointment is blended with 0.001-50wt.%, preferably 0.01-10wt.% based on the total amount of the external preparation of one or more compounds selected from a group consisting of 2-hydroxybutyric acid, 3-hydroxybutyric acid, 4-hydroxybutyric acid and sodium salts thereof as an active ingredient to give an external preparation of suppressing melanogenesis, having high safety and excellent selectivity. n COPYRIGHT: (C)1992,JPO&Japio |