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publicationDate 1992-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H044896-A
titleOfInvention Production of cephalexin
abstract PURPOSE: To industrially and efficiently obtain the title cephalexin useful as an antibiotic in a biological method by adding penicillin acylase produced by the Xanthomonas to a reaction system. n CONSTITUTION: When 7-aminodesacetoxycephalosporonic acid is reacted with phenylglycin and reactive derivative thereof, Penicillin acylase produced by Xanthomonas sp. YT-1099 strain (FERM P-11401) is added to the reaction system to provide the aimed cephalexin. Furthermore, the above-mentioned enzyme is preferably obtained from a cultured mixture obtained by culturing the above- mentioned microbial strain in a nutrient medium at pH 6-7 and 25-30°C for 12-20 hr. n COPYRIGHT: (C)1992,JPO&Japio
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