| abstract |
PURPOSE: To obtain the subject safe medical composition, food additives or beverage showing a high effect by using a dioxabicyclo[3.3.0]octane derivative in combination with an antioxidizing agent and improving various effects, especially cholesterol-reducing effect of the octane derivatives. n CONSTITUTION: (A) A compound represented by the formula (R 1 -R 6 are H or 1-3C alkyl. R 1 and R 2 and/or R 4 and R 5 form methylene or ethylene; 1-n are 0 or 1) and showing respectively recognized effects such as Δ 5 -unsaturated enzyme inhibitory effect, improvement of liver function, cholesterol-reducing effect, carcinogenesis inhibition and drunken sickness prevention, e.g. sesamin, sesaminol, episesamin, episesaminol or sesamolin is blended with (B) an anti- oxidizing agent such as tocopherol having a high-safety preferably in a ratio of 0.001-1000 pts.wt (B) based on 1 pts.wt. (A), thus giving the objective medical composition, food additives or beverage in which the above-mentioned effects, especially cholesterol-reducing effect of the active component (A) are improved. n COPYRIGHT: (C)1992,JPO&Japio |