http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04330071-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-54 |
| filingDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d6dd591d83ddc49a12452c5481a1372 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb64850dd0153af7ffcf78e30c40b05f |
| publicationDate | 1992-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04330071-A |
| titleOfInvention | Triphenylethylene derivative and medicinal composition containing the same derivative and having inhibitory action on tumor |
| abstract | PURPOSE: To obtain a new compound excellent in the inhibitory action on tumor. n CONSTITUTION: A compound shown by formula I [R 1 and R 3 are lower alkyl, lower cycloalkyl or is bonded to adjoining nitrogen to form heterocyclic ring; R 3 is H, OH, R 5 COO, OPO(OH) 2 (R 5 is lower alkyl, lower cycloalkyl or substituted aryl; R 6 is lower alkyl or lower alkylcarbonyl); R is lower alkyl or lower cycloalkyl; Ar is 3,4-methylenedioxyphenyl] such as 1-[4-(3- dimethylamino-2-hydroxypropoxy)phenyl]-1-(4-hydroxyphenyl)-2-(3,4- methylenedioxyphenyl)-1-butene. The compound shown by formula I is obtained by reacting a compound shown by formula II with a compound shown by formula III in a medium containing a reducing titanium compound to give a compound, reacting this compound with an oxysilane derivative to give a compound shown by formula IV and reacting this compound with a proper amine compound. n COPYRIGHT: (C)1992,JPO&Japio |
| priorityDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.