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filingDate 1991-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a887c0276a4433f0e713d88f1df1c76
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publicationDate 1992-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H04312520-A
titleOfInvention Penetration enhancement with multicomponent system of n-aliphatic pyrrolidone with lower alcohol
abstract PURPOSE: To prepare a composition capable of enhancing the penetration of an active drug through skin without irritating the skin. n CONSTITUTION: This composition comprises a safe and an effective amount of a lipophilic or a hydrophilic active ingredient contained in a new penetrability enhancing vehicle. The vehicle contains (i) 0.01-20wt.% N-aliphatic pyrrolidone, (ii) 5-75wt.% lower alkanol (e.g. ethanol or propanol), (iii) 5.0-94.99wt.% carrier such as water and (iv) 0-20wt.% cell-enveloped diordering compound, e.g. methyl laurate or glycerol monolaurate and a mixture thereof. n COPYRIGHT: (C)1992,JPO
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011507904-A
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