| abstract |
PURPOSE: To obtain a new compound useful as a treating and preventing medicine for allergic diseases, inflammatory diseases, diseases of circulatory organs, etc., having antagonism to leukotriene. n CONSTITUTION: A compound shown by formula I (X and Y are H or acyl; R is phenyl, phthalidylmethyl, etc.) such as 2,4-diamino-[E]-6-[2-(4- methoxycarbonylphenyl)ethenyl]-1,3,5-triazine. The compound shown by formula I, for example, is obtained by condensing a compound shown by formula II with an aldehyde shown by the formula R 1 -CHO in the presence of an acid or a base when R is CH=CH-R 1 . n COPYRIGHT: (C)1992,JPO&Japio |