http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04297422-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fb9f44db08d1c42a53f3d28eaae416f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 |
| filingDate | 1991-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dd5949e68c7cdbd7edaacad5285c190 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3883147a140eb065c1a326afbe5b05be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0079ee539b2b8160a4aefdb85aa717f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2863f36aa713e0aafeb8110922688c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ae6af387be939bc5687b424e055d5de |
| publicationDate | 1992-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04297422-A |
| titleOfInvention | Antirheumatic agent |
| abstract | PURPOSE: To obtain an antirheumatic agent, containing a steroidal compound having the steroidal skeleton in which the 21-position is substituted with an acylthio group or amide group derived from an N-acylamino acid having a specific structure as an active ingredient and capable of exhibiting high antirheumatic effects with hardly any side effects. n CONSTITUTION: An antirheumatic agent containing a 21-substituted steroidal compound expressed by the formula (R 1 is H, alkyl, alkoxy or phenyl; R 2 is OH or acyloxy; R 3 is H or alkyl or R 2 and R 3 together may form alkylmdenednoxy; X 1 and X 2 are H or halogen; indicates that the steric configuration may be either of α or β and the broken line between the 1-and 2-positions indicates that the bond may be double bond) {e.g. 9-fluoro-21-[2(formylamino)-4- methylthio-1-oxobutylthio]-11β, 17-dihydroxy-16α-methylpregna-1,4-diene-3,20- dione} as an active ingredient. The aforementioned medicine is capable of inhibiting production of interleukin from inflammatory cells which are causes for formation of main morbid states and further exacerbation thereof in chronic rheumarthritis. n COPYRIGHT: (C)1992,JPO&Japio |
| priorityDate | 1991-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458394811 |
Total number of triples: 18.