http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04295478-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620ecb9324409347c27e96b6071503ee |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 1991-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37cdbd1c3757f53e2be2a3fd25e84f10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94abed5728c69fc3f53415f62be71e17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d89846df8128952f5e942b76ec537b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e22751816f23a19ff963b89a1af1cd3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aca43da55c0d8da24f3439a06db74c69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc46b9e1547fe426dde0ad4a29b4509a |
publicationDate | 1992-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H04295478-A |
titleOfInvention | Imidazo(4,5-b)pyridine derivative or its salt |
abstract | PURPOSE: To provide a new compound having angiotensin II antagonistic action and useful for the prevention and treatment of hypertension, chronic heart failure, etc. n CONSTITUTION: The compound of formula I [R 1 is halogen-substituted lower alkyl, lower alkenyl or lower alkynyl; R 2 is H or lower alkyl; one of R 3 , R 4 and R 5 is group of formula II (R 6 is H or aralkyl) and the others are H], e.g. 7-methyl-2-(3,3,3-trifluoropropyl)-3-[[2'-(N-triphenylmethyltetrazol-5-yl) biphenyl-4- yl]methyl-3H-imidazo[4,5-b]pyridine. The compound of formula I can be produced by reacting an imidazo[4,5-b]pyridine of formula III with biphenylmethyl halide of formula IV in a solvent (e.g. DMF) in the presence of a base (e.g. sodium methoxide). n COPYRIGHT: (C)1992,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105237340-A |
priorityDate | 1991-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.