http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04275297-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f0ff51562c131a9bbcfa3cec9c4916a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3d769ec1031b59fcca3c151074a3a9d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0095 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
| filingDate | 1991-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d10906d6b0e17129c12fc65e51f06335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb155b8d5df77595c7f49b239c0815ca |
| publicationDate | 1992-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04275297-A |
| titleOfInvention | New steroid derivative |
| abstract | PURPOSE: To provide a new steroid derivative composed of 3-oxo-1,4-pregnadiene derivative, free from glucocorticoid action, having highly selective strong local antiinflammatory action and useful as antiinflammatory agent having low side effect. n CONSTITUTION: The objective steroid derivative of formula III [X is H or F; R 1 is H, OH or methyl; R 2 and R 3 are H, OH, O(CH 2 ) n SiR 3 (R is alkyl; n is 0 or 1-6), etc.; R 4 is alkyl] [e.g. methyl(20S)-acetoxy-11β,17-dihydroxy-3-oxo-1,4- pregnadien-21-oate] can be produced by treating a steroid having hydroxymethyl ketone group at 17-site and expressed by formula I (e.g. prednisolone) in anhydrous methanol in the presence of anhydrous copper acetate at ordinary temperature to obtain a trihydroxy compound of formula II (methyl 20-11β,17,20- trihydroxy-3-oxo-1,4-pregnadien-21-oate) and acylating, alkylating or silylating the 20-OH group of the product. n COPYRIGHT: (C)1992,JPO&Japio |
| priorityDate | 1991-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.