| abstract |
PURPOSE: To provide a new benzyl phenyl ketone derivative useful as intermediate for various chemicals, pharmaceuticals, agricultural chemicals, etc. n CONSTITUTION: The compound of formula I [X is H, halogen, lower alkyl, lower haloalkyl, CN, lower alkoxy, lower haloalkoxy, lower alkoxyalkyl, phenoxy, etc.; (m) is integer of 1-5; Y is H, OH, halogen, CN, NO 2 , lower alkyl, lower alkoxy, lower haloalkoxy, lower alkenyloxy, lower alkoxycarbonyl, etc.; (n) is integer of 1-4; Z is CN, lower alkoxycarbonyl or aminosulfonyl which may have one or two substituents (lower alkyl); when Y is 4-CN and Z is H, X is not H, 4-Cl or 4-CN], e.g. 3-cyanobenzyl phenyl ketone. The compound can be produced by reacting a compound of formula III (R is lower alkyl) with a compound of formula II in a polar aprotic solvent in the presence of 1-2mol (based on 1mol of the compound of formula III) of a base. n COPYRIGHT: (C)1992,JPO&Japio |