http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04244021-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 |
| filingDate | 1991-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd8ad28b6c68925088993ec6131797f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c386a3c80b68ecd4a200b8e86956b7cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86300c7927497249f524bd06bc5daee7 |
| publicationDate | 1992-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04244021-A |
| titleOfInvention | Use of mixed micelle |
| abstract | PURPOSE: To enable orally safe treatment, especially to newborn babies by using vitamin K 1 in the form of an aqueous solution of mixed micelle comprising a cholanoic acid salt and phospholipid. n CONSTITUTION: Vitamin K 1 is used in the form of an aqueous solution of mixed micelle in production of oral vitamin K 1 formulation in order to orally administer vitamin K 1 to newborn babies. A cholanoic acid salt (especially glycocholic acid) and phospholipid (especially lecithin) are used as the mixed micelle. For example, glycocolic acid is dissolved in purified water Ph. Eur by using sodium hydroxide and pH of the solution is adjusted to 5.5 by using hydrochloric acid. Lecithin is dissolved in sodium glycocholate solution while stirring and vitamin K 1 is added thereto while stirring. Purified water Ph.Eur. is added to the resultant vitamin K 1 mixed micelle solution and pH of the solution is adjusted to 6.0 by using hydrochloric acid and purified water Ph. Eur. is added to the solution and the solution is filtered to provide a vitamin K 1 mixed micelle solution. n COPYRIGHT: (C)1992,JPO |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105997869-A |
| priorityDate | 1990-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.