http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04234380-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-92 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-92 |
| filingDate | 1991-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28d7dd45560b6067e39bb23f23345fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7edea6d4962c38defe89f4556d41897b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2197f06bc3661631fc35bd8530acaa49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bffc6ce0397f740188ea7be804e158e |
| publicationDate | 1992-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04234380-A |
| titleOfInvention | Preparation of 6-acyl, 7-acyl and 6,7-diacyl homologue of forskolin and its intermediate |
| abstract | PURPOSE: To easily and economically obtain the highly pure compound by acylating intermediate with 1,9-o-isopropylidene protected and then eliminating the protecting group. n CONSTITUTION: After introducing 1,9-o-isopropylidene protecting group into forskolin, the compound of formula I is obtained by common acylation and/or acyl-transfer method. The objective compound of formula II is obtained by treating at 0-80°C, preferably 25-60°C, for 72 hours, preferably 1-24 hours, in the solution of pH1.0-3.5, preferably pH1.0-1.3, and then eliminating 1,9-o- isopropylidene protecting group. In formula I, R 1 and R 2 are each OH, acetoxy or OCOC(R 3 ) 2 (CH 2 ) n X [R 3 is H or alkyl; (n) is 0-10; X is H, halogen, alkyl, NR 4 R 5 (when R 4 and R 5 are the same, these are each H or alkyl and when these are different, R 4 is H and R 5 is alkyl, aryl or aralkyl), etc.]; (a) is additional bonding. n COPYRIGHT: (C)1992,JPO |
| priorityDate | 1990-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.