http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04228094-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b0f615b92cd3bb66e8ea41483a2dc63 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-14 |
| filingDate | 1991-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f717f09d87595dad1524d6ddcd14b23 |
| publicationDate | 1992-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04228094-A |
| titleOfInvention | Production of epoxy alcohol of high optical purity |
| abstract | PURPOSE: To efficiently produce the subject compound used for synthesizing a raw material, etc., for a physiologically active substance by allowing a lipase and carboxylic acids to act on an epoxidation reaction mixture containing a chiral epoxy alcohol and its enantiomer, and separating the formed ester. n CONSTITUTION: This method for enhancing optical purity of an epoxidation reaction mixture containing a major amount of the first chiral epoxy alcohol of the formula (R 1 to R 4 are each H, a 1-18C alkyl, an aryl or an aralkyl), etc., and a miner amount of the second chiral epoxy alcohol, which is a enantiomer of the first chiral alcohol, comprises reacting the epoxidation reaction mixture with a lipase enzyme, and a carboxylic acid derivative such as an enol ester, a saturated ester and a carboxylic acid in an amount and a condition, in which the second chiral epoxy alcohol is preferentially converted to an epoxy ester, and separating the first chiral epoxy alcohol from the epoxy ester to provide the objective compound. n COPYRIGHT: (C)1992,JPO |
| priorityDate | 1990-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.