http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04221383-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4c14a3c2e541ec9969ff17176c1426d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 1990-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf65fcef77e087243e6a879eebfeefcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82f463d4ef5737535d12af11bf680a75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7751cd46477ca924a2258166fd694b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66bc422aebe3696386c6127f389b9172 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fba820d1959c690d23a6350d025aa7a |
| publicationDate | 1992-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04221383-A |
| titleOfInvention | Pyrazino(1,2-i)(1,7)phenanthroline-9-carboxylic acid compound and production thereof |
| abstract | PURPOSE: To provide the subject new pyrazinophenanthrolinecarboxylic acid compounds useful as an antibacterial agent and effective also to methicillin- resistant Staphylococcus aureus. n CONSTITUTION: Compounds of formula I (R 1 is 1-4C alkyl, phenyl, etc.; R 2 is H, methyl, etc.; X is F, Cl, etc.), salts thereof or hydrates thereof, e.g. 6- fluoro-11-(2,4-difluorophenyl)-1,3,4,8-11,12,13,13a-octahydro-2-methyl-8, 12-dioxo-2H- pyrazino[1,2-i][1,7]phenanthroline-9-carboxylic acid. These compounds can be obtained by reacting a 4-oxoquinoline-3-carboxylic acid of formula II (Y is X; R 3 is H or 1-4C alkyl) with an N-benzylethylenediamine of formula III in the presence of a base (preferably pyrimidine, etc.), subsequently debenzylating the resultant reaction product and then reacting the resultant compound of formula IV with a 4-bromocrotonic acid derivative. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011031744-A1 |
| priorityDate | 1990-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.