http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04217658-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cebc9740ef706cde29e885504f274ffa |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 |
| filingDate | 1990-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b1a1927a0beb05dedfe996a308d2d8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7ddc4ef9643c47978e7f2bd23f62133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d945be6896644c116124c13b93bc27b6 |
| publicationDate | 1992-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04217658-A |
| titleOfInvention | Racemization of optically active carboxylic acid ester |
| abstract | PURPOSE: To racemize an optically active carboxylic acid ester in high yield in a short time by bringing the ester into contact with an amine compound in a specific mixed solvent. n CONSTITUTION: An optically active carboxylic acid ester of formula R 1 - COS-(CH 2 )n-CH(R 2 )-COO-R 3 (R 1 is alkyl, aralkyl or aryl; R 2 and R 3 are alkyl; n is 1 or 2) is brought into contact with an amine compound at 50-200°C in a mixture of an unsaturated carboxylic acid ester of formula CH 2 =C(R 2 )-COO-R 3 or CH 2 =CH-CH(R 2 )-COO-R 3 (e.g. methyl methacrylate) and a bipolar aprotic solvent (e.g. N,N-dimethylformamide). The use of the above mixed solvent as the reaction solvent is effective for efficiently eliminating thiocarboxylic acid from the optically active carboxylic acid ester, stabilizing the thiocarboxylic acid and enabling the readdition of the thiocarboxylic acid to the unsaturated carboxylic acid ester to obtain the racemic carboxylic acid ester. n COPYRIGHT: (C)1992,JPO&Japio |
| priorityDate | 1990-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.