| abstract |
PURPOSE: To provide a carbonylation process for the preparation of an amide characterized by the use of a carbonylation catalyst comprising a specified, nitrogen-containing phosphine ligand. n CONSTITUTION: In the presence of a catalyst system comprising a) a source of a Group VIII metal, such as Pd, b) a phosphine having an aromatic substituent which contains an imino nitrogen atom, e.g. bisphenyl (2-pyridyl)phosphine, and c) a protonic acid such as p-toluenesulfonic acid, an acetylenically or olefinically unsaturated compound is reacted with carbon monoxide and a nitrogen compound selected from ammonia and a primary or secondary amine or amide. n COPYRIGHT: (C)1992,JPO |