| abstract |
PURPOSE: To obtain in a high yield the titled compound which is a precursor for fungicides and fungi growth controlling agents, by reacting specified ketone with isothiolonium salt under phase-transfer catalytic reaction conditions, thus evading the generation of mercaptans with unpleasant odor. n CONSTITUTION: In the presence of a phase-transfer reaction catalyst (e.g. quaternary ammonium salt), compound of formula I (A is t-butyl, or optionally substituted phenyl, biphenyl, 1,2,3,4-tetrahydronaphthyl, thienyl, indalyl, etc.), e.g. 2-bromo-3-chloropropyl-4-chlorophenyl ketone, are reacted with compounds of formula II (R is alkyl, alkenyl, alkynyl, phenyl, biphenyl, etc.; X is halogen or sulfate), e.g. 4-chlorophenylthioethylisothiolonium chloride to give compound of formula III, e.g. 1-(4-chlorobenzoyl)-1-(4-chlorophenylthioethylthio)cyclopropane. n COPYRIGHT: (C)1992,JPO |