| abstract |
NEW MATERIAL: A compound of formula I [Ar is formula II (V is H, halogen, alkyl, alkoxy, CF 3 or NO 2 ; u is 1-3; X, Y are CF 3 or CHF; Z, W are CH 2 , O, CHOH or CHF; m, n, p, q, and are 0 or 1; R 1 is H or alkyl; and R 2 , R 3 are alkyl)], their acid addition salts, and where applicable the geometric and optical isomers and racemic mixtures thereof. n EXAMPLE: 2-(3-Chlorophenyl)-1-[3-(dimethylamino)phenyl] ethanone. n USE: Pharmaceutical agents for alleviating various memory dysfunctins. n PROCESS: For example, a compound of formula I is obtained by reacting a compound of formula III (Hal stands for Cl, Br or I) with a compound of formula IV (R 4 is carboxylic acid derivative). n COPYRIGHT: (C)1992,JPO |