http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04200392-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1990-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77fc1ea44f9e472fdc5793643c43b979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19dafe6a4f9b34947229b74e501ee3f8 |
| publicationDate | 1992-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04200392-A |
| titleOfInvention | Optical resolution with enzyme |
| abstract | PURPOSE: To obtain an optical resolution product in high purity and yield under mild condition by treating a specific racemic compound with an SH enzyme (an enzyme having -SH group at the active site) originated from animal or vegetable. n CONSTITUTION: Racemic 4-acyloxy-4-ethyl-6,6-(ethylenedioxy)-7,8-dihydro-1H- pyrano[3,4-f]indolidine-3,10(4H)-dione (A) of formula I (R is alkyl) is suspended in an amount of 0.1-5wt.% in water or a mixture of water and an organic solvent such as ethyl acetate to obtain a suspension (B). The liquid B is added with 1-10 pts.wt. (based on 1 pt.wt. of the component A) of an SH enzyme (C) such as papain and reacted at 5-60°C for 10-48 hr. The obtained reaction product (D) is filtered, concentrated and purified to obtain (S)-4-acyloxy-4- ethyl-6,6-(ethylenedioxy)-7,8-dihydro-1H-pyrano[3,4-f]indolidine-3,10(4H)-dione of formula II by optical resolution. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0845464-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1528062-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0845464-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1236728-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1236728-A2 |
| priorityDate | 1990-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.