http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04193827-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 1990-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2496a4f7b8cdd90d7e32f5f15aade28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f71041d760d03116907e2be31ea95312 |
| publicationDate | 1992-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H04193827-A |
| titleOfInvention | Treating agent for chronic myelogenous leukemia |
| abstract | PURPOSE: To obtain the title treating agent having low toxicity and low accumulation of toxicity by continuous administration, comprising ubenimex or a salt thereof as an active ingredient. n CONSTITUTION: A treating agent for chronic myelogenous leukemia comprising N-[(2S, 3R)-3-amino-2-hydroxy-4-phenylbutyryl(7)-(L)-leucine (ubenimex) or a salt thereof as an active ingredient. A dose of the compound is 5-500mg per adult daily in oral administration and 1-300mg in parenteral administration. Preferable, a patient is previously dosed with a treating agent for chronic myelogenous leukemia such as busulfan and, at a point of time when number of leukocytes is reduced to ≤10,000/μl, the treating agent has to be administered. The treating agent is especially effective at an early period of disease, and high and complete hematologic remission is obtained and cytogenetic remission is also observable in high ratio. n COPYRIGHT: (C)1992,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9700677-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6245813-B1 |
| priorityDate | 1990-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.