http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04124166-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03d0f52bb4069f8a19d70dcfb697c67a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10 |
filingDate | 1990-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd052fcda21ad42eab4118b84c058c5 |
publicationDate | 1992-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H04124166-A |
titleOfInvention | Amphiphatic compound and liposome containing the same |
abstract | NEW MATERIAL:The compound of formula I to formula III [R<1> and R<2> are 8-24C straight or branched alkyl or acyl which may have substituent and unsaturated group; R<3n>, R<3(n+1)>, R<3m> and R<3(m+1)> are residue of side chain of alpha-amino acid; the asymmetric C in the molecule may be racemic or optically active; the carboxyl group at the molecular terminal may form a salt with a proper cation]. USE:A membrane-constituting component capable of forming a stable single- membrane liposome causing little leakage of included drug and resistant to association, coagulation and precipitation. PREPARATION:The compounds of formula I to formula III can be produced by using the substituted glycerol of formula IV as a raw material, condensing an amino acid having protected amino group or carboxyl group with a proper condensation agent and reacting with succinic acid, thereby successively introducing the amino acid part and the succinic acid part to the starting compound. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005232054-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4649841-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010513354-A |
priorityDate | 1990-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.