http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04124166-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03d0f52bb4069f8a19d70dcfb697c67a
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-22
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10
filingDate 1990-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd052fcda21ad42eab4118b84c058c5
publicationDate 1992-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H04124166-A
titleOfInvention Amphiphatic compound and liposome containing the same
abstract NEW MATERIAL:The compound of formula I to formula III [R<1> and R<2> are 8-24C straight or branched alkyl or acyl which may have substituent and unsaturated group; R<3n>, R<3(n+1)>, R<3m> and R<3(m+1)> are residue of side chain of alpha-amino acid; the asymmetric C in the molecule may be racemic or optically active; the carboxyl group at the molecular terminal may form a salt with a proper cation]. USE:A membrane-constituting component capable of forming a stable single- membrane liposome causing little leakage of included drug and resistant to association, coagulation and precipitation. PREPARATION:The compounds of formula I to formula III can be produced by using the substituted glycerol of formula IV as a raw material, condensing an amino acid having protected amino group or carboxyl group with a proper condensation agent and reacting with succinic acid, thereby successively introducing the amino acid part and the succinic acid part to the starting compound.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005232054-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4649841-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010513354-A
priorityDate 1990-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397365
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Total number of triples: 30.