http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04103572-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d6256baf554e46784d8daa478a2ddc6 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate | 1990-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3168e74e35ca468311f790da9a80f5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af9334a83d79250b2610712e2e4b8a58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_605d27abf79811c659ae698c121acbb1 |
publicationDate | 1992-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H04103572-A |
titleOfInvention | 4-phenyl-2-(1-piperazinyl)pyridine derivative |
abstract | NEW MATERIAL:A compound shown by formula I [X is CH 2 CO, CH 2 CH(OH) or CH=CH; R 1 is lower alkyl; R 2 and R 3 are H, halogen, lower alkyl or lower alkoxy (n) is 1-4] and a salt thereof. n EXAMPLE: 2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-10-hydroxy-5,6,7,8,9,10- hexahydrocycloocta[b]pyridine. n USE: A medicine having excellent psychotropic action and inhibitory action on central nervous system. n PREPARATION: A compound shown by formula II (Y is halogen) is made to react with a piperazine compound shown by formula III in a solventless state or in a solvent (e.g. dimethyl sulfoxide) preferably in the presence of a base (e.g. triethylamine) at 40-200°C to give a compound shown by formula I. n COPYRIGHT: (C)1992,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7507732-B2 |
priorityDate | 1990-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.